Established in 2004, the Museum at the Lowest Place on Earth (MuLPE) stands as a testament to the rich archaeological and historical heritage of the Southern Ghor area near the Dead Sea in Jordan. Born from the visionary collaboration between the Department of Antiquities and Dr. Konstantinos D. Politis, the museum is the culmination of decades of archaeological excavations and preservation efforts. Initially referred to as "Lot’s Museum" due to its proximity to the Sanctuary of Lot at Dayr ʿAyn ʿAbatah, it evolved to encompass a broader scope, chronicling over 10,000 years of human history in the region.

Located north of As Safi, the museum's architecture was inspired by fossil Ammonite shells found in the area, with the design entrusted to Jordanian architect George Hakim. Spread across approximately 2,000 x 500 meters, the museum features a central exhibition hall housing artifacts from various historical periods, ranging from the Paleolithic Age to the Late Islamic Age. Thematic units within the museum explore topics such as the geography of the area, early civilizations, the Nabataean presence, the story of Lot, and modern-day life around the Dead Sea. Additionally, the museum offers educational programs, hosts temporary exhibitions, and provides facilities including a library, multimedia room, cafe, museum shop, conservation laboratory, and storage rooms for archaeological finds. Serving as both a cultural repository and a research hub, the MuLPE plays a vital role in preserving and showcasing the archaeological heritage of the Southern Ghor region.